Inbreeding Depression
Inbreeding Depression
14,90€
The presentation addresses the topic of inbreeding and inbreeding depression, serving as a summary of already known background information. Dr. Manz begins with an introduction to Generatio GmbH, a company specializing in genetic identity determination and parentage verification, which introduced litter registration for breeding animals in 2010. Through a merger, the company’s technical portfolio was expanded.
He further explains how genetic identification works without fingerprints or chip information by using DNA profiles. He illustrates the basics of evolution, such as genetic recombination and mutations during meiosis, which create new genetic variations, including the effects of inbreeding in the form of increased risk of genetic disorders and the reduction of genetic diversity, leading to inbreeding depression across entire populations.
The presentation emphasizes the importance of avoiding high levels of inbreeding and the need for tools to manage genetic diversity. These include DNA-based methods like SNP typing and next-generation sequencing. Dr. Manz also introduces the use of STR marker profiles for parentage verification, which have already been established within the WUSV’s DNA program.
Finally, the calculation of a diversity coefficient based on allele frequencies is discussed, which describes the genetic composition of an animal but has no relation to traditional pedigree data.